Interferons: Success in anti-viral immunotherapy

F Lin, HA Young - Cytokine & growth factor reviews, 2014 - Elsevier
The interferons (IFNs) are glycoproteins with strong antiviral activities that represent one of
the first lines of host defense against invading pathogens. These proteins are classified into
three groups, Type I, II and III IFNs, based on the structure of their receptors on the cell
surface. Due to their ability to modulate immune responses, they have become attractive
therapeutic options to control chronic virus infections. In combination with other drugs, Type I
IFNs are considered as “standard of care” in suppressing Hepatitis C (HCV) and Hepatitis B …