An algorithm for the grading of activity in chronic hepatitis C

P Bedossa, T Poynard - Hepatology, 1996 - journals.lww.com
Histological activity reflects the global assessment of basic necroinflammatory lesions and is
a criterion of major importance in chronic hepatitis C. The aim of this study was to propose
and test the accuracy of a simple algorithm that generates a single activity score based on
basic pathological features. A panel of 10 pathologists reviewed 363 chronic hepatitis C liver
biopsies and graded the activity of hepatitis according to their own experience (reference
activity). Then, a consensual algorithm on the grading of activity was established by the 10 …