Clinical experience gives rise to the impression that there are differences in fracture healing
in different age groups. It is evident that fractures heal more efficiently in children than in
adults. However, minimal objective knowledge exists to evaluate this assumption. Temporal,
spatial, and cellular quantitative and qualitative interrelationships, as well as signaling
molecules and extracellular matrix have not been comprehensively and adequately
elucidated for fracture healing in the geriatric skeleton. The biological basis of fracture …