Objective To describe the development of progressive multifocal leukoencephalopathy
(PML) in patients with rheumatoid arthritis (RA) treated with rituximab. Design Case study.
Setting Clinical care for patients with rheumatologic diseases. Most were referred to
academic centers for care after diagnosis (Washington University, St Louis, Missouri;
Karolinska Insitute, Stockholm, Sweden; and Royal Melbourne Hospital, Melbourne,
Australia) while one was cared for in a neurology practice in Dallas, Texas, with consultation …