[HTML][HTML] Identification of a novel Na+-independent acidic amino acid transporter with structural similarity to the member of a heterodimeric amino acid transporter family …

H Matsuo, Y Kanai, JY Kim, A Chairoungdua… - Journal of Biological …, 2002 - ASBMB
We identified a novel Na+-independent acidic amino acid transporter designated AGT1
(aspartate/glutamatetransporter 1). AGT1 exhibits the highest sequence similarity (48%
identity) to the Na+-independent small neutral amino acid transporter Asc (asc-type amino
acid transporter)-2 a member of the heterodimeric amino acid transporter family presumed to
be associated with unknown heavy chains (Chairoungdua, A., Kanai, Y., Matsuo, H., Inatomi,
J., Kim, DK, and Endou, H.(2001) J. Biol. Chem. 276, 49390–49399). The cysteine residue …