[HTML][HTML] Developmental changes of CD34 expression by murine hematopoietic stem cells
T Ito, F Tajima, M Ogawa - Experimental hematology, 2000 - Elsevier
OBJECTIVE: It has been reported that fetal murine hematopoietic stem cells are CD34+,
whereas adult stem cells are CD34−. We sought to delineate the developmental changes of
CD34 expression by hematopoietic stem cells and carried out systematic analysis of long-
term engrafting cells in the bone marrow and/or blood of perinatal, juvenile, and adult mice.
MATERIALS AND METHODS: To obtain information on the total population of stem cells, we
prepared CD34+ and CD34− populations of mononuclear cells without prior enrichment and …
whereas adult stem cells are CD34−. We sought to delineate the developmental changes of
CD34 expression by hematopoietic stem cells and carried out systematic analysis of long-
term engrafting cells in the bone marrow and/or blood of perinatal, juvenile, and adult mice.
MATERIALS AND METHODS: To obtain information on the total population of stem cells, we
prepared CD34+ and CD34− populations of mononuclear cells without prior enrichment and …