Large amounts of energy are required to maintain the signaling activities of CNS cells.
Because of the fine-grained heterogeneity of brain and the rapid changes in energy
demand, it has been difficult to monitor rates of energy generation and consumption at the
cellular level and even more difficult at the subcellular level. Mechanisms to facilitate energy
transfer within cells include the juxtaposition of sites of generation with sites of consumption
and the transfer of∼ P by the creatine kinase/creatine phosphate and the adenylate kinase …