The role of oxidative stress in glaucoma
A Izzotti, A Bagnis, SC Saccà - Mutation Research/Reviews in Mutation …, 2006 - Elsevier
DNA damage is related to a variety of degenerative diseases such as cancer,
atherosclerosis and neurodegenerative diseases, depending on the tissue affected.
Increasing evidence indicates that reactive oxygen species (ROS) play a key role in the
pathogenesis of primary open angle glaucoma (POAG), the main cause of irreversible
blindness worldwide. Oxidative DNA damage is significantly increased in the ocular
epithelium regulating aqueous humor outflow, ie, the trabecular meshwork (TM), of …
atherosclerosis and neurodegenerative diseases, depending on the tissue affected.
Increasing evidence indicates that reactive oxygen species (ROS) play a key role in the
pathogenesis of primary open angle glaucoma (POAG), the main cause of irreversible
blindness worldwide. Oxidative DNA damage is significantly increased in the ocular
epithelium regulating aqueous humor outflow, ie, the trabecular meshwork (TM), of …