[HTML][HTML] Chronic wasting disease agents in nonhuman primates
B Race, KD Meade-White, K Phillips… - Emerging infectious …, 2014 - ncbi.nlm.nih.gov
B Race, KD Meade-White, K Phillips, J Striebel, R Race, B Chesebro
Emerging infectious diseases, 2014•ncbi.nlm.nih.govChronic wasting disease is a prion disease of cervids. Assessment of its zoonotic potential is
critical. To evaluate primate susceptibility, we tested monkeys from 2 genera. We found that
100% of intracerebrally inoculated and 92% of orally inoculated squirrel monkeys were
susceptible, but cynomolgus macaques were not, suggesting possible low risk for humans.
critical. To evaluate primate susceptibility, we tested monkeys from 2 genera. We found that
100% of intracerebrally inoculated and 92% of orally inoculated squirrel monkeys were
susceptible, but cynomolgus macaques were not, suggesting possible low risk for humans.
Abstract
Chronic wasting disease is a prion disease of cervids. Assessment of its zoonotic potential is critical. To evaluate primate susceptibility, we tested monkeys from 2 genera. We found that 100% of intracerebrally inoculated and 92% of orally inoculated squirrel monkeys were susceptible, but cynomolgus macaques were not, suggesting possible low risk for humans.
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