Generation of macrophages from peripheral blood monocytes in the rhesus monkey

AE Rozner, SV Dambaeva, JG Drenzek… - Journal of …, 2009 - Elsevier
Macrophages are found in tissues throughout the body and are important immune cells,
however, these tissue macrophages are difficult to collect and study. Therefore, the ability to
differentiate macrophages from peripheral blood precursors is an important research tool.
Macrophage differentiation has been well studied in humans, but differentiation in the non-
human primate is poorly characterized. Using human models is not always feasible for
invasive experimental studies and, therefore, developing reliable protocols for the non …