Neurotrophic factor therapy for Parkinson's disease

SB Rangasamy, K Soderstrom, RAE Bakay… - Progress in brain …, 2010 - Elsevier
Parkinson's disease (PD) is a chronic, progressive neurodegenerative movement disorder
for which there is currently no effective therapy. Over the past several decades, there has
been a considerable interest in neuroprotective therapies using trophic factors to alleviate
the symptoms of PD. Neurotrophic factors (NTFs) are a class of molecules that influence a
number of neuronal functions, including cell survival and axonal growth. Experimental
studies in animal models suggest that members of neurotrophin family and GDNF family of …