Type 1 diabetes intervention trials 2007: where are we and where are we going?
Current Opinion in Endocrinology, Diabetes and Obesity, 2007•journals.lww.com
The inability to cure type 1 diabetes underscores the complex pathophysiology of the
disease, and our poor knowledge of the precise etiological triggers and immunological
mechanisms which culminate in the disease. While ongoing efforts to test individual agents
with potential to ameliorate diabetes are needed, combination therapies employing multiple
safe agents are likely to be the future of type 1 diabetes intervention studies.
disease, and our poor knowledge of the precise etiological triggers and immunological
mechanisms which culminate in the disease. While ongoing efforts to test individual agents
with potential to ameliorate diabetes are needed, combination therapies employing multiple
safe agents are likely to be the future of type 1 diabetes intervention studies.
Summary
The inability to cure type 1 diabetes underscores the complex pathophysiology of the disease, and our poor knowledge of the precise etiological triggers and immunological mechanisms which culminate in the disease. While ongoing efforts to test individual agents with potential to ameliorate diabetes are needed, combination therapies employing multiple safe agents are likely to be the future of type 1 diabetes intervention studies.
Lippincott Williams & Wilkins