[HTML][HTML] Atypical expression of mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase in subcutaneous adipose tissue of male rats
S Thumelin, C Kohl, J Girard, JP Pégorier - Journal of lipid research, 1999 - ASBMB
The mRNAs encoding mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase (mtHMG-
CoA synthase), the rate limiting enzyme in ketone body production, are highly expressed in
subcutaneous (SC) and, to a lesser extent, in peri-epididymal (PE) rat adipose tissues. This
atypical mtHMG-CoA synthase gene expression is dependent on the age (from 9 weeks of
age) and sex (higher in male than in female) of the rats. In contrast, the expression of
mtHMG-CoA synthase in SC adipose deposit is independent of the nutritional state (fed …
CoA synthase), the rate limiting enzyme in ketone body production, are highly expressed in
subcutaneous (SC) and, to a lesser extent, in peri-epididymal (PE) rat adipose tissues. This
atypical mtHMG-CoA synthase gene expression is dependent on the age (from 9 weeks of
age) and sex (higher in male than in female) of the rats. In contrast, the expression of
mtHMG-CoA synthase in SC adipose deposit is independent of the nutritional state (fed …