[HTML][HTML] Inflammation and retinopathy of prematurity
O Dammann - Acta paediatrica (Oslo, Norway: 1992), 2010 - ncbi.nlm.nih.gov
Acta paediatrica (Oslo, Norway: 1992), 2010•ncbi.nlm.nih.gov
Retinopathy of prematurity (ROP) is a disorder of retinal vasoproliferation that occurs mainly
in extremely preterm infants [1]. The long-term visual outcome among children with ROP
includes a prominently increased risk of a range of visual disabilities [2]. Understanding the
etiology and pathogenesis of ROP is crucial for the design of strategies to prevent and treat
this potentially disabling disease. Less than a decade ago, one review included the
statement “only low birth weight, low gestational age, and supplemental oxygen therapy …
in extremely preterm infants [1]. The long-term visual outcome among children with ROP
includes a prominently increased risk of a range of visual disabilities [2]. Understanding the
etiology and pathogenesis of ROP is crucial for the design of strategies to prevent and treat
this potentially disabling disease. Less than a decade ago, one review included the
statement “only low birth weight, low gestational age, and supplemental oxygen therapy …
Retinopathy of prematurity (ROP) is a disorder of retinal vasoproliferation that occurs mainly in extremely preterm infants [1]. The long-term visual outcome among children with ROP includes a prominently increased risk of a range of visual disabilities [2]. Understanding the etiology and pathogenesis of ROP is crucial for the design of strategies to prevent and treat this potentially disabling disease.
Less than a decade ago, one review included the statement “only low birth weight, low gestational age, and supplemental oxygen therapy following delivery have been consistently associated with disease”[3]. This statement was made despite the recognition by others that other antecedents might be important, including insufficient levels of vitamin E, indomethacin treatment for patent ductus arteriosus, hypercapnia, maternal aspirin use, and transfusion of blood and blood products or the need for such transfusions [4].
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