Prenatal farm exposure is related to the expression of receptors of the innate immunity and to atopic sensitization in school-age children

MJ Ege, C Bieli, R Frei, RT van Strien, J Riedler… - Journal of Allergy and …, 2006 - Elsevier
BACKGROUND: There is increasing evidence that environmental exposures determining
childhood illnesses operate early in life. Prenatal exposure to a farming environment
through the mother might also play an important role. OBJECTIVE: We sought to investigate
the role of maternal exposures to environments rich in microbial compounds for the
development of atopic sensitization, asthma, and corresponding alterations in the innate
immune system in offspring. METHODS: In the children of the cross-sectional Prevention of …