Gene expression profile of ovarian serous papillary carcinomas: identification of metastasis-associated genes

E Bignotti, RA Tassi, S Calza, A Ravaggi… - American journal of …, 2007 - Elsevier
OBJECTIVE: The purpose of this study was to identify genes that are highly differentially
expressed in metastatic serous papillary ovarian tumors (MET) when compared with primary
ovarian serous carcinomas (OSPC). STUDY DESIGN: An oligonucleotide microarray with
probe sets complementary to> 14,500 human genes was used to determine whether
patterns of gene expression may differentiate OSPC from MET in 31 snap-frozen serous
papillary ovarian carcinomas (ie, 14 primary OSPC and 17 omental metastasis [MET]) …