Impact of bacteria in dairy products and of the intestinal microflora on the genotoxic and carcinogenic effects of heterocyclic aromatic amines
S Knasmüller, H Steinkellner, AM Hirschl… - Mutation Research …, 2001 - Elsevier
This article gives a short overview on the present state of knowledge of the effects of the
intestinal microflora on the health hazards of heterocyclic aromatic amines (HAs). Results of
single cell gel electrophoresis assays with conventional, germ free and human flora
associated rats indicate that the presence of intestinal microorganisms strongly enhances
the induction of DNA-damage in colon and liver cells by IQ. Furthermore, it was found that
supplementation of the feed with Lactobacilli attenuates the induction of colon cancer by this …
intestinal microflora on the health hazards of heterocyclic aromatic amines (HAs). Results of
single cell gel electrophoresis assays with conventional, germ free and human flora
associated rats indicate that the presence of intestinal microorganisms strongly enhances
the induction of DNA-damage in colon and liver cells by IQ. Furthermore, it was found that
supplementation of the feed with Lactobacilli attenuates the induction of colon cancer by this …