Modification of shear modulus and creep compliance of fibrin clots by fibronectin

GW Kamykowski, DF Mosher, L Lorand, JD Ferry - Biophysical chemistry, 1981 - Elsevier
Shear moduli and creep compliances have been measured for four types of clots of human
fibrin (about 7 mg ml) clotted with and without human plasma fibronectin (usually 1.2 mg ml).
Fine clots (with little lateral aggregation of the fibrin protofibrils) were formed at pH 8.5, ionic
strength 0.45; coarse clots (with substantial lateral aggregation) were formed at pH 7.5, ionic
strength 0.15; in both cases with and without ligation by fibrinougase. In fine clots, the
addition of fibronectin without ligation scarcely affected the shear modulus; with ligation, the …