[HTML][HTML] Characterization of fibronectin assembly by platelets adherent to adsorbed laminin‐111
Background: Various types of laminin (LN) are ubiquitous components of basement
membrane and exposed to blood upon localized damage of vascular endothelial cells.
Fibronectin is a plasma protein that is insolubilized into fibrils in a regulated fashion by, for
example, lysophosphatidic acid (LPA)‐stimulated fibroblasts or platelets spread on
supportive adhesive ligands. Objective: To study assembly of plasma fibronectin by LPA‐
activated platelets adherent to LN‐111 via α6β1 integrin. Results: Platelets adherent to LN …
membrane and exposed to blood upon localized damage of vascular endothelial cells.
Fibronectin is a plasma protein that is insolubilized into fibrils in a regulated fashion by, for
example, lysophosphatidic acid (LPA)‐stimulated fibroblasts or platelets spread on
supportive adhesive ligands. Objective: To study assembly of plasma fibronectin by LPA‐
activated platelets adherent to LN‐111 via α6β1 integrin. Results: Platelets adherent to LN …