Immunisation against heterologous type II collagen induces arthritis in mice

JS Courtenay, MJ Dallman, AD Dayan, A Martin… - Nature, 1980 - nature.com
JS Courtenay, MJ Dallman, AD Dayan, A Martin, B Mosedale
Nature, 1980nature.com
The induction of polyarthritis in rats by intradermal immunisation with homologous or
heterologous type II collagen in complete or incomplete Freund's adjuvant was reported
recently by Trentham et al. 1. We have now produced a similar disease in certain strains of
mice.
Abstract
The induction of polyarthritis in rats by intradermal immunisation with homologous or heterologous type II collagen in complete or incomplete Freund's adjuvant was reported recently by Trentham et al.1. We have now produced a similar disease in certain strains of mice.
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