[HTML][HTML] Characterization of DP103, a novel DEAD box protein that binds to the Epstein-Barr virus nuclear proteins EBNA2 and EBNA3C
AT Grundhoff, E Kremmer, O Tureci, A Glieden… - Journal of Biological …, 1999 - ASBMB
The Epstein-Barr virus-encoded nuclear antigens EBNA2 and EBNA3C both interact with
the cellular transcription factor RBP-Jκ and modulate the expression of several shared target
genes, suggesting a tight cooperation in latently infected cells. In a survey for additional
cellular factors that bind to EBNA2 as well as EBNA3C, we have isolated and characterized
DP103, a novel human member of the DEAD box family of putative ATP-dependent RNA
helicases. The interaction with DP103 is mediated by amino acids (aa) 121–213 of EBNA2 …
the cellular transcription factor RBP-Jκ and modulate the expression of several shared target
genes, suggesting a tight cooperation in latently infected cells. In a survey for additional
cellular factors that bind to EBNA2 as well as EBNA3C, we have isolated and characterized
DP103, a novel human member of the DEAD box family of putative ATP-dependent RNA
helicases. The interaction with DP103 is mediated by amino acids (aa) 121–213 of EBNA2 …