A bird's-eye view of Crohn's disease.

AH Robb-Smith - Proceedings of the Royal Society of Medicine, 1971 - ncbi.nlm.nih.gov
AH Robb-Smith
Proceedings of the Royal Society of Medicine, 1971ncbi.nlm.nih.gov
In attempting to provide a bird's-eye view of Crohn's disease I am not sure that the
ornithological simile is apposite, for birds have a remarkable acuity of vision and my views
on the nature of this disease are not much clearer than they were thirty years ago when I
was working at St Bartholomew's Hospital with Professor Hadfield. As a pathologist, by
nature of the disease I mean three things: the morphological charac-ters on which one can
make a histological diagnosis; the morphogenesis of the conditionthe interpretation of the …
In attempting to provide a bird's-eye view of Crohn's disease I am not sure that the ornithological simile is apposite, for birds have a remarkable acuity of vision and my views on the nature of this disease are not much clearer than they were thirty years ago when I was working at St Bartholomew's Hospital with Professor Hadfield.
As a pathologist, by nature of the disease I mean three things: the morphological charac-ters on which one can make a histological diagnosis; the morphogenesis of the conditionthe interpretation of the structural changes that determine the histological appearances; and lastly the etiology, the causative factors that induce these changes. The morphology ofregional enteritis is well known; there are ideas about its morphogenesis, but the etiology, so far as I am aware, is still obscure.
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