Quantitative assessment of thrombus burden predicts the outcome of treatment for venous thrombosis: a systematic review
RD Hull, VJ Marder, AF Mah, RK Biel… - The American journal of …, 2005 - Elsevier
PURPOSE: Clot-burden change in patients receiving anticoagulant therapy, by predicting
subsequent recurrent venous thromboembolism, may provide a clinically relevant surrogate
endpoint of prognostic importance. The validity of this objective measure is yet to be
established. METHODS: A PubMed search was performed to retrieve articles published up
to December 2003. We identified 11 randomized trials reported from 1990 to 2003 that met
our study identification and selection criteria. Anticoagulant therapy subsequently approved …
subsequent recurrent venous thromboembolism, may provide a clinically relevant surrogate
endpoint of prognostic importance. The validity of this objective measure is yet to be
established. METHODS: A PubMed search was performed to retrieve articles published up
to December 2003. We identified 11 randomized trials reported from 1990 to 2003 that met
our study identification and selection criteria. Anticoagulant therapy subsequently approved …