[HTML][HTML] Red cell ICAM-4 is a novel ligand for platelet-activated αIIbβ3 integrin
P Hermand, P Gane, M Huet, V Jallu, C Kaplan… - Journal of Biological …, 2003 - ASBMB
ICAM-4 (LW blood group glycoprotein) is an erythroid-specific membrane component that
belongs to the family of intercellular adhesion molecules and interacts in vitrowith different
members of the integrin family, suggesting a potential role in adhesion or cell interaction
events, including hemostasis and thrombosis. To evaluate the capacity of ICAM-4 to interact
with platelets, we have immobilized red blood cells (RBCs), platelets, and ICAM-Fc fusion
proteins to a plastic surface and analyzed their interaction in cell adhesion assays with …
belongs to the family of intercellular adhesion molecules and interacts in vitrowith different
members of the integrin family, suggesting a potential role in adhesion or cell interaction
events, including hemostasis and thrombosis. To evaluate the capacity of ICAM-4 to interact
with platelets, we have immobilized red blood cells (RBCs), platelets, and ICAM-Fc fusion
proteins to a plastic surface and analyzed their interaction in cell adhesion assays with …