High expression of p40tax and pro-inflammatory cytokines and chemokines in the lungs of human T-lymphotropic virus type 1-related bronchopulmonary disorders
Y Yamazato, A Miyazato, K Kawakami, S Yara… - Chest, 2003 - Elsevier
Study objective Human T-lymphotropic virus type 1 (HTLV-1) is closely associated with the
development of certain pulmonary diseases, such as bronchiolitis, although the pathologic
mechanism remains unclear. To elucidate the pathogenesis of HTLV-1–associated
bronchopulmonary disorders, we analyzed the relationship between expression of p40 tax,
a regulatory component of HTLV-1 that stimulates various host genes, and synthesis of pro-
inflammatory cytokines and chemokines by cells in BAL fluid (BALF) obtained from HTLV-1 …
development of certain pulmonary diseases, such as bronchiolitis, although the pathologic
mechanism remains unclear. To elucidate the pathogenesis of HTLV-1–associated
bronchopulmonary disorders, we analyzed the relationship between expression of p40 tax,
a regulatory component of HTLV-1 that stimulates various host genes, and synthesis of pro-
inflammatory cytokines and chemokines by cells in BAL fluid (BALF) obtained from HTLV-1 …