The power and the promise of DNA methylation markers
PW Laird - Nature Reviews Cancer, 2003 - nature.com
Nature Reviews Cancer, 2003•nature.com
The past few years have seen an explosion of interest in the epigenetics of cancer. This has
been a consequence of both the exciting coalescence of the chromatin and DNA
methylation fields, and the realization that DNA methylation changes are involved in human
malignancies. The ubiquity of DNA methylation changes has opened the way to a host of
innovative diagnostic and therapeutic strategies. Recent advances attest to the great
promise of DNA methylation markers as powerful future tools in the clinic.
been a consequence of both the exciting coalescence of the chromatin and DNA
methylation fields, and the realization that DNA methylation changes are involved in human
malignancies. The ubiquity of DNA methylation changes has opened the way to a host of
innovative diagnostic and therapeutic strategies. Recent advances attest to the great
promise of DNA methylation markers as powerful future tools in the clinic.
Abstract
The past few years have seen an explosion of interest in the epigenetics of cancer. This has been a consequence of both the exciting coalescence of the chromatin and DNA methylation fields, and the realization that DNA methylation changes are involved in human malignancies. The ubiquity of DNA methylation changes has opened the way to a host of innovative diagnostic and therapeutic strategies. Recent advances attest to the great promise of DNA methylation markers as powerful future tools in the clinic.
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