Out-of-hospital administration of intravenous glucose-insulin-potassium in patients with suspected acute coronary syndromes: the IMMEDIATE randomized controlled …
HP Selker, JR Beshansky, PR Sheehan, JM Massaro… - Jama, 2012 - jamanetwork.com
Context Laboratory studies suggest that in the setting of cardiac ischemia, immediate
intravenous glucose-insulin-potassium (GIK) reduces ischemia-related arrhythmias and
myocardial injury. Clinical trials have not consistently shown these benefits, possibly due to
delayed administration. Objective To test out-of hospital emergency medical service (EMS)
administration of GIK in the first hours of suspected acute coronary syndromes (ACS).
Design, Setting, and Participants Randomized, placebo-controlled, double-blind …
intravenous glucose-insulin-potassium (GIK) reduces ischemia-related arrhythmias and
myocardial injury. Clinical trials have not consistently shown these benefits, possibly due to
delayed administration. Objective To test out-of hospital emergency medical service (EMS)
administration of GIK in the first hours of suspected acute coronary syndromes (ACS).
Design, Setting, and Participants Randomized, placebo-controlled, double-blind …