[HTML][HTML] Antiobesity and lipid-lowering effects of Bifidobacterium spp. in high fat diet-induced obese rats
HM An, SY Park, DK Lee, JR Kim, MK Cha… - Lipids in health and …, 2011 - Springer
HM An, SY Park, DK Lee, JR Kim, MK Cha, SW Lee, HT Lim, KJ Kim, NJ Ha
Lipids in health and disease, 2011•SpringerBackground Recent studies have reported the preventive effects of probiotics on obesity.
Among commensal bacteria, bifidobacteria is one of the most numerous probiotics in the
mammalian gut and are a type of lactic acid bacteria. The aim of this study was to assess the
antiobesity and lipid-lowering effects of Bifidobacterium spp. isolated from healthy Korean
on high fat diet-induced obese rats. Methods Thirty-six male Sprague-Dawley rats were
divided into three groups as follows:(1) SD group, fed standard diet;(2) HFD group, fed high …
Among commensal bacteria, bifidobacteria is one of the most numerous probiotics in the
mammalian gut and are a type of lactic acid bacteria. The aim of this study was to assess the
antiobesity and lipid-lowering effects of Bifidobacterium spp. isolated from healthy Korean
on high fat diet-induced obese rats. Methods Thirty-six male Sprague-Dawley rats were
divided into three groups as follows:(1) SD group, fed standard diet;(2) HFD group, fed high …
Background
Recent studies have reported the preventive effects of probiotics on obesity. Among commensal bacteria, bifidobacteria is one of the most numerous probiotics in the mammalian gut and are a type of lactic acid bacteria. The aim of this study was to assess the antiobesity and lipid-lowering effects of Bifidobacterium spp. isolated from healthy Korean on high fat diet-induced obese rats.
Methods
Thirty-six male Sprague-Dawley rats were divided into three groups as follows: (1) SD group, fed standard diet; (2) HFD group, fed high fat diet; and (3) HFD-LAB group, fed high fat diet supplemented with LAB supplement (B. pseudocatenulatum SPM 1204, B. longum SPM 1205, and B. longum SPM 1207; 108 ~ 109 CFU). After 7 weeks, the body, organ, and fat weights, food intake, blood serum levels, fecal LAB counts, and harmful enzyme activities were measured.
Results
Administration of LAB reduced body and fat weights, blood serum levels (TC, HDL-C, LDL-C, triglyceride, glucose, leptin, AST, ALT, and lipase levels), and harmful enzyme activities (β-glucosidase, β-glucuronidase, and tryptophanase), and significantly increased fecal LAB counts.
Conclusion
These data suggest that Bifidobacterium spp. used in this study may have beneficial antiobesity effects.
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