Mechanisms of inhaled fine particulate air pollution–induced arterial blood pressure changes
Background Epidemiologic studies suggest a positive association between fine particulate
matter and arterial blood pressure, but the results have been inconsistent. Objectives We
investigated the effect of ambient particles on systemic hemodynamics during a 5-hr
exposure to concentrated ambient air particles (CAPs) or filtered air (FA) in conscious
canines. Methods Thirteen dogs were repeatedly exposed via permanent tracheostomy to
CAPs (358.1±306.7 μg/m3, mean±SD) or FA in a crossover protocol (55 CAPs days, 63 FA …
matter and arterial blood pressure, but the results have been inconsistent. Objectives We
investigated the effect of ambient particles on systemic hemodynamics during a 5-hr
exposure to concentrated ambient air particles (CAPs) or filtered air (FA) in conscious
canines. Methods Thirteen dogs were repeatedly exposed via permanent tracheostomy to
CAPs (358.1±306.7 μg/m3, mean±SD) or FA in a crossover protocol (55 CAPs days, 63 FA …