Natural helper cells: a new player in the innate immune response against helminth infection
S Koyasu, K Moro, M Tanabe, T Takeuchi - Advances in immunology, 2010 - Elsevier
The Th2-type immune response, characterized by the production of IL-4, IL-5, and IL-13, is a
critical immune response against helminths invading cutaneous or mucosal sites. Th2
cytokines are induced soon after helminth infection, even before a pathogen-specific
adaptive immune response is established. Although the expulsion and clearance of
helminths usually requires pathogen-specific Th2-mediated immunity, early induction of Th2
cytokines during the innate immune phase is important for host protection from helminth …
critical immune response against helminths invading cutaneous or mucosal sites. Th2
cytokines are induced soon after helminth infection, even before a pathogen-specific
adaptive immune response is established. Although the expulsion and clearance of
helminths usually requires pathogen-specific Th2-mediated immunity, early induction of Th2
cytokines during the innate immune phase is important for host protection from helminth …