Monoamine oxidase (MAO) B deaminates a number of biogenic and dietary amines and
plays an important role in many biological processes. Among hormonal regulations of MAO
B, we have recently found that retinoic acid (RA) significantly activates both MAO B promoter
activity and mRNA expression in a human neuroblastoma BE (2) C cell line. RA activates
MAO B promoter in both concentration-and time-dependent manners, which is mediated
through retinoic acid receptor α (RARα) and retinoid X receptor α (RXRα). There are four …