[HTML][HTML] Alkyl-dihydroxyacetonephosphate synthase: fate in peroxisome biogenesis disorders and identification of the point mutation underlying a single enzyme …
ECJM de Vet, L IJlst, W Oostheim, RJA Wanders… - Journal of Biological …, 1998 - ASBMB
Peroxisomes play an indispensible role in ether lipid biosynthesis as evidenced by the
deficiency of ether phospholipids in fibroblasts and tissues from patients suffering from a
number of peroxisomal disorders. Alkyl-dihydroxyacetonephosphate synthase, a
peroxisomal enzyme playing a key role in the biosynthesis of ether phospholipids, contains
the peroxisomal targeting signal type 2 in a N-terminal cleavable presequence. Using a
polyclonal antiserum raised against alkyl-dihydroxyacetonephosphate synthase, levels of …
deficiency of ether phospholipids in fibroblasts and tissues from patients suffering from a
number of peroxisomal disorders. Alkyl-dihydroxyacetonephosphate synthase, a
peroxisomal enzyme playing a key role in the biosynthesis of ether phospholipids, contains
the peroxisomal targeting signal type 2 in a N-terminal cleavable presequence. Using a
polyclonal antiserum raised against alkyl-dihydroxyacetonephosphate synthase, levels of …