Incident renal events and risk factors in autosomal dominant polycystic kidney disease: a population and family-based cohort followed for 22 years
E Dicks, P Ravani, D Langman… - Clinical Journal of the …, 2006 - journals.lww.com
For determination of the incidence of renal events in autosomal dominant polycystic kidney
disease (ADPKD) all patients who had ADPKD and attended nephrology/urology clinics in
Newfoundland in 1981 were identified, and members of 18 families who were at 50% risk for
inheriting ADPKD were followed prospectively for 22 yr, including research clinics at 6-yr
intervals. Time to hypertension treatment, stage 3 chronic kidney disease (CKD), ESRD, and
death was measured, and the impact of genotype, gender, gender of parent who transmitted …
disease (ADPKD) all patients who had ADPKD and attended nephrology/urology clinics in
Newfoundland in 1981 were identified, and members of 18 families who were at 50% risk for
inheriting ADPKD were followed prospectively for 22 yr, including research clinics at 6-yr
intervals. Time to hypertension treatment, stage 3 chronic kidney disease (CKD), ESRD, and
death was measured, and the impact of genotype, gender, gender of parent who transmitted …