Kidney volume and functional outcomes in autosomal dominant polycystic kidney disease

AB Chapman, JE Bost, VE Torres… - Clinical Journal of the …, 2012 - journals.lww.com
Results After a mean follow-up of 7.9 years, stage 3 CKD was attained in 30.7% of the
enrollees. Using baseline htTKV, negative correlations with GFR increased from− 0.22 at
baseline to− 0.65 at year 8. In multivariable analysis, a baseline htTKV increase of 100 cc/m
significantly predicted the development of CKD within 8 years with an odds ratio of 1.48
(95% confidence interval: 1.29, 1.70). In receiver operator characteristic curve analysis,
baseline htTKV of 600 cc/m most accurately defined the risk of developing stage 3 CKD …