Factors for glaucoma progression and the effect of treatment: the early manifest glaucoma trial

MC Leske, A Heijl, M Hussein… - Archives of …, 2003 - jamanetwork.com
Objective To assess factors for progression in the Early Manifest Glaucoma Trial (EMGT),
including the effect of EMGT treatment. Setting/Participants Two hundred fifty-five open-
angle glaucoma patients randomized to argon laser trabeculoplasty plus topical betaxolol or
no immediate treatment (129 treated; 126 controls) and followed up every 3 months.
Methods Progression was determined by perimetric and photographic optic disc criteria.
Patient-based risk of progression was evaluated using Cox proportional hazard regression …