Effect of pretreatment with omalizumab on the tolerability of specific immunotherapy in allergic asthma
M Massanari, H Nelson, T Casale, W Busse… - Journal of Allergy and …, 2010 - Elsevier
BACKGROUND: Although specific immunotherapy is a valuable treatment option for patients
with allergic asthma, the potential for systemic allergic reactions has limited its use,
especially for patients with symptomatic disease. OBJECTIVE: To evaluate omalizumab's
effect on the tolerability of specific immunotherapy in patients with symptomatic persistent
asthma not adequately controlled with inhaled corticosteroids. METHODS: This multicenter,
double-blind, parallel-group study randomized patients to treatment with omalizumab or …
with allergic asthma, the potential for systemic allergic reactions has limited its use,
especially for patients with symptomatic disease. OBJECTIVE: To evaluate omalizumab's
effect on the tolerability of specific immunotherapy in patients with symptomatic persistent
asthma not adequately controlled with inhaled corticosteroids. METHODS: This multicenter,
double-blind, parallel-group study randomized patients to treatment with omalizumab or …