Proliferative epithelial lesions in the smaller caliber pancreatic ducts and ductules have
been the subject of numerous morphologic, clinical, and genetic studies; however, a
standard nomenclature and diagnostic criteria for classifying these lesion have not been
established. To evaluate the uniformity of existing systems for grading duct lesions in the
pancreas, 35 microscopic slides with 35 representative duct lesions were sent to eight
expert pathologists from the United States, Canada, and Europe. Kappa values for …