Infection of mice with Listeria monocytogenes induces a robust innate inflammatory
response that restricts bacterial growth in the liver and spleen prior to the development of
protective T cell responses. Ly6C hi monocytes contribute to the innate immune response
following L. monocytogenes infection and in their absence, mice rapidly succumb to
infection. Emigration of Ly6C hi monocytes from the bone marrow into the circulation is the
first step in their recruitment to sites of L. monocytogenes infection and is triggered by CCL2 …