Development of blood vessels takes place via two subsequent processes, vasculogenesis
and angiogenesis. During vasculogenesis, formation of first blood vessels is achieved by
differentiation of hemangiogenic stem cells from pluripotent mesenchymal cells, while during
angiogenesis new blood vessels form from already existing vessels. The combination of our
data with those from the literature leads us to depict the chronological steps of cell
differentiation in the mesenchymal core of placental villi during vasculogenesis and …