Glomerular filtration barrier
B Haraldsson, M Jeansson - Current opinion in nephrology and …, 2009 - journals.lww.com
B Haraldsson, M Jeansson
Current opinion in nephrology and hypertension, 2009•journals.lww.comGlomerular diseases account for 90% of chronic kidney disease requiring dialysis and
transplantation at an annual cost of $20 billion in the USA. In clinical practice, we lack
specific treatment of these diseases, giving us plenty of room for improvement. Future
research should be directed toward deeper understanding of the signaling pathways
involved in different conditions of proteinuria, the cross-talk between cell types in the
glomerulus, and the identification of novel targets for treatment of acquired kidney disease.
transplantation at an annual cost of $20 billion in the USA. In clinical practice, we lack
specific treatment of these diseases, giving us plenty of room for improvement. Future
research should be directed toward deeper understanding of the signaling pathways
involved in different conditions of proteinuria, the cross-talk between cell types in the
glomerulus, and the identification of novel targets for treatment of acquired kidney disease.
Summary
Glomerular diseases account for 90% of chronic kidney disease requiring dialysis and transplantation at an annual cost of $20 billion in the USA. In clinical practice, we lack specific treatment of these diseases, giving us plenty of room for improvement. Future research should be directed toward deeper understanding of the signaling pathways involved in different conditions of proteinuria, the cross-talk between cell types in the glomerulus, and the identification of novel targets for treatment of acquired kidney disease.
Lippincott Williams & Wilkins