[PDF][PDF] Regulating the immune response to transplants: a role for CD4+ regulatory cells?

H Waldmann, S Cobbold - Immunity, 2001 - cell.com
Immunity, 2001cell.com
Transplantation of cells and organs is now a rapidly could, on adoptive transfer, suppress
graft rejection by evolving therapeutic modality for the correction of a naive T cells. Although
these initial studies were conwide range of disease states. This has been made posducted
with skin grafts mismatched for multiple minor sible by the development of powerful
immunosupprestransplantation antigens, CD4 regulatory T cells were sant drugs that can
stave off the rejection process. also found in mice tolerating heart grafts mismatched
Transplantation of cells and organs is now a rapidly could, on adoptive transfer, suppress graft rejection by evolving therapeutic modality for the correction of a naive T cells. Although these initial studies were conwide range of disease states. This has been made posducted with skin grafts mismatched for multiple minor sible by the development of powerful immunosupprestransplantation antigens, CD4 regulatory T cells were sant drugs that can stave off the rejection process. also found in mice tolerating heart grafts mismatched
cell.com