[HTML][HTML] Upregulation of FcϵRI on human basophils by IgE antibody is mediated by interaction of IgE with FcϵRI
D MacGlashan Jr, LM Lichtenstein… - Journal of allergy and …, 1999 - Elsevier
Background: IgE is now known to upregulate the expression of FcϵRI on human basophils.
It is not known which receptor on basophils mediates this process of upregulation. Objective:
We sought to determine whether galectin-3, FcϵRII (CD23), or FcϵRI were involved in the
upregulation of FcϵRI by IgE. Methods: The role of galectin-3 was examined by measuring
the influence of α-lactose on upregulation. Basophils were examined for expression of
FcϵRII (CD23) by flow cytometry and messenger (m) RNA expression. Functional …
It is not known which receptor on basophils mediates this process of upregulation. Objective:
We sought to determine whether galectin-3, FcϵRII (CD23), or FcϵRI were involved in the
upregulation of FcϵRI by IgE. Methods: The role of galectin-3 was examined by measuring
the influence of α-lactose on upregulation. Basophils were examined for expression of
FcϵRII (CD23) by flow cytometry and messenger (m) RNA expression. Functional …