The alpha subunit of the human IgE receptor (FcERI) is sufficient for high affinity IgE binding.

J Hakimi, C Seals, JA Kondas, L Pettine… - Journal of Biological …, 1990 - ASBMB
The alpha subunit of the FcERI binds IgE with high affinity. Previous studies have
demonstrated that alpha subunit expression requires the presence of beta and/or gamma
subunits, and it is not known how these two subunits contribute to the ability of the alpha
subunit to bind IgE. In this report, we describe the expression and characterization of a
human chimeric alpha subunit. The data demonstrate that high affinity IgE binding does not
require the presence of the beta and/or gamma subunits and that this activity is localized to …