[HTML][HTML] Metabolic connections during apoptotic cell engulfment

CZ Han, KS Ravichandran - Cell, 2011 - cell.com
Cell, 2011cell.com
Billions of cells die via apoptosis every day and are swiftly removed. When a phagocyte
engulfs an apoptotic cell, it essentially doubles its cellular contents, raising the question of
how a phagocyte may manage the excess metabolic load. This Minireview discusses
phagocyte cellular metabolism, the digestion of the ingested apoptotic cell, and the impact of
these processes on engulfment.
Billions of cells die via apoptosis every day and are swiftly removed. When a phagocyte engulfs an apoptotic cell, it essentially doubles its cellular contents, raising the question of how a phagocyte may manage the excess metabolic load. This Minireview discusses phagocyte cellular metabolism, the digestion of the ingested apoptotic cell, and the impact of these processes on engulfment.
cell.com