Emergence of dendritic cells in rupture-prone regions of vulnerable carotid plaques

A Yilmaz, M Lochno, F Traeg, I Cicha, C Reiss… - Atherosclerosis, 2004 - Elsevier
Dendritic cells (DC), which are critically involved in various immunological disorders, were
detected in atherosclerotic plaques in 1995. Since DC might be related to the immunological
processes in atherosclerosis (AS), we analyzed the emergence of DC and other
inflammatory cells in different stages of AS. Serial cross-sections of 44 carotid specimens
were immunohistochemically analyzed for the presence of DC, T cells, macrophages, and
HLA-DR. Atherosclerotic specimens were histologically defined as initial lesions, advanced …