[HTML][HTML] Intravenous apoA-I/lecithin discs increase pre-β-HDL concentration in tissue fluid and stimulate reverse cholesterol transport in humans
MN Nanjee, CJ Cooke, R Garvin, F Semeria… - Journal of lipid …, 2001 - ASBMB
The extent to which plasma HDL concentration regulates reverse cholesterol transport
(RCT) is not known. The principal acceptors of unesterified cholesterol (UC) from cultured
cells are small pre-β-HDL, which we have shown increase in plasma during intravenous
infusion of apolipoprotein AI/phosphatidylcholine (apoA-I/PC) discs in humans. We have
now examined the effects on tissue fluid HDL and RCT. ApoA-I/PC or proapoA-I/PC discs
were infused into 16 healthy males. Eleven had been given intravenous radiocholesterol to …
(RCT) is not known. The principal acceptors of unesterified cholesterol (UC) from cultured
cells are small pre-β-HDL, which we have shown increase in plasma during intravenous
infusion of apolipoprotein AI/phosphatidylcholine (apoA-I/PC) discs in humans. We have
now examined the effects on tissue fluid HDL and RCT. ApoA-I/PC or proapoA-I/PC discs
were infused into 16 healthy males. Eleven had been given intravenous radiocholesterol to …