[HTML][HTML] A conserved mRNA export machinery coupled to pre-mRNA splicing
R Reed, E Hurt - Cell, 2002 - cell.com
R Reed, E Hurt
Cell, 2002•cell.comRecent advances have led to a new understanding of how mRNAs are exported from the
nucleus to the cytoplasm. This process requires a heterodimeric mRNA export receptor that
is part of an elaborate machinery conserved from yeast to humans. Export of mRNAs is
coupled to upstream steps in gene expression, such as pre-mRNA splicing, and to
downstream events, including nonsense-mediated decay.
nucleus to the cytoplasm. This process requires a heterodimeric mRNA export receptor that
is part of an elaborate machinery conserved from yeast to humans. Export of mRNAs is
coupled to upstream steps in gene expression, such as pre-mRNA splicing, and to
downstream events, including nonsense-mediated decay.
Abstract
Recent advances have led to a new understanding of how mRNAs are exported from the nucleus to the cytoplasm. This process requires a heterodimeric mRNA export receptor that is part of an elaborate machinery conserved from yeast to humans. Export of mRNAs is coupled to upstream steps in gene expression, such as pre-mRNA splicing, and to downstream events, including nonsense-mediated decay.
cell.com