Due to the intracellular nature of mycobacterial infections, little attention has been paid to the
possible extracellular role that neutrophils might play in tuberculosis. The recent discovery of
neutrophil extracellular traps (NETs), composed of DNA and antimicrobial proteins, 1
introduces a new perspective to our understanding of the mechanism used by the innate
immune system to contain and kill microorganisms. In this study, we tested in vitro whether
Mycobacterium tuberculosis, an intracellular pathogen, can induce NETs formation and if …