Transition of highly specific microRNA expression patterns in association with discrete maturation stages of human granulopoiesis.
SM Sun, MK Dijkstra, AC Bijkerk… - British journal of …, 2011 - search.ebscohost.com
British journal of haematology, 2011•search.ebscohost.com
The article presents a study which characterizes MicroRNA (miRNA) expression patterns in
stages of normal human neutrophilic development. It states that the study collected
granulocytes in different stages of granulocytic differentiation, isolated RNA from them and
profiled their miRNA expression. Furthermore, It is revealed through principal component
analysis that there are sharp distinctions of expressed miRNAs between the granulocytic
maturation stages.
stages of normal human neutrophilic development. It states that the study collected
granulocytes in different stages of granulocytic differentiation, isolated RNA from them and
profiled their miRNA expression. Furthermore, It is revealed through principal component
analysis that there are sharp distinctions of expressed miRNAs between the granulocytic
maturation stages.
Abstract
The article presents a study which characterizes MicroRNA (miRNA) expression patterns in stages of normal human neutrophilic development. It states that the study collected granulocytes in different stages of granulocytic differentiation, isolated RNA from them and profiled their miRNA expression. Furthermore, It is revealed through principal component analysis that there are sharp distinctions of expressed miRNAs between the granulocytic maturation stages.
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