[HTML][HTML] The human glycine receptor subunit α3: Glra3 gene structure, chromosomal localization, and functional characterization of alternative transcripts
The neuronal glycine receptor is a ligand-gated chloride channel composed of ligand
binding α and structural β polypeptides. Homology screening of a human fetal brain cDNA
library resulted in the identification of two alternative splice variants of the glycine receptor
α3 subunit. The amino acid sequence predicted for the α3L variant was largely identical to
the corresponding rat subunit. In contrast, the novel splice variant α3K lacked the coding
sequence for 15 amino acids located within the cytoplasmic loop connecting …
binding α and structural β polypeptides. Homology screening of a human fetal brain cDNA
library resulted in the identification of two alternative splice variants of the glycine receptor
α3 subunit. The amino acid sequence predicted for the α3L variant was largely identical to
the corresponding rat subunit. In contrast, the novel splice variant α3K lacked the coding
sequence for 15 amino acids located within the cytoplasmic loop connecting …